Noteworthy Read
CBD May Help Address “Digital Era Fatigue” (The Marijuana Herald)
A new review suggests CBD may have potential for addressing “digital era fatigue,” a proposed syndrome linked to excessive screen time, cognitive tiredness, mood disruption, sleep problems, and stress. The authors point to CBD’s effects on inflammation, oxidative stress, serotonin signaling, and sleep regulation as evidence of its therapeutic utility for these types of issues.
More Noteworthy Reading
When Do Psychedelics Go Too Far? (Medium)
Andrew Weisse examines the cultural and clinical risks that can emerge when psychedelic use is framed as a universal solution or pushed beyond appropriate boundaries. In this article, he raises questions about overuse, weak screening, commercialization, spiritual bypassing, and the need for clearer norms around when psychedelic experiences may do more harm than good.
Read more
View more in Psychedelics
Common Problems in Psychedelic Science (Sage Journals)
This review outlines recurring issues in psychedelic research, including small sample sizes, weak blinding, inflated effect sizes, expectancy effects, and media hype. The paper is a useful reminder that enthusiasm around psychedelics needs to be matched with stronger methods, transparent reporting, and more careful claims about clinical promise.
Read more
View more in Psychedelics
Time to Embrace the Whole: Magic Mushrooms Instead of Single-Molecule Psilocybin in Research and Therapy (Natural Products Research)
This paper argues that psychedelic research should pay more attention to whole psilocybin-containing mushrooms rather than focusing almost exclusively on isolated psilocybin. The authors suggest that other mushroom compounds may influence therapeutic effects, safety, or tolerability, though controlled studies are needed to test whether whole-mushroom preparations offer meaningful advantages.
Read more
View more in Psychedelics
Research Round-Up
Endocannabinoid System and Skeletal Muscle Health: Insights From CBD (Molecular Metabolism)
A new review examines how the endocannabinoid system may influence skeletal muscle health, including metabolism, inflammation, mitochondrial function, and muscle repair. The paper uses CBD as a framework for exploring cannabinoid-related pathways in muscle biology, looking at research that connects cannabinoids with metabolic and musculoskeletal health.
Read more
View more in Endocannabinoid System
A heartfelt thank you to all of the CBD brands whose generous support allows Project CBD to shine a light on the latest plant medicine research and bring these important stories to our community.
The post Project CBD Newsletter: CBD for Digital Era Fatigue, Psychedelics Research Risks and Methods, Whole-Mushroom Psilocybin, and the Endocannabinoid System’s Role in Muscle Health appeared first on Project CBD.