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Project CBD Newsletter: Cannabis inflammation research, CBD and gut-liver health, pain relief with CBD:THC formulations, and more

This week’s newsletter covers the latest in plant medicine research, including cannabis’s dual effects on inflammation, CBD’s potential for gut-liver health, pain relief from balanced cannabinoid formulations, and more.

Noteworthy Read

Cannabinoid Use Is Linked to Both Pro- and Anti-Inflammatory Effects, Massive Review Finds (PsyPost)

A large-scale review found that cannabis can have both calming and activating effects on inflammation depending on context, dose, and individual biology, highlighting the complexity of how cannabinoids interact with the immune system and the endocannabinoid systems of different individuals.

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Research Round-Up

CBD Modulates the Gut–Liver Axis: Therapeutic Implications (PubMed)

A new review explores how CBD may support the gut–liver connection by calming inflammation, influencing the microbiome, and helping regulate metabolic signaling. These effects point to potential benefits for conditions linked to digestive and liver health.

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Painkilling Effects of a 1:1 CBD:THC Oral Formulation (Journal of Pain)

A clinical study found that a balanced CBD:THC formulation helped reduce pain levels in patients, supporting the idea that combining cannabinoids may offer more effective relief than isolated compounds alone.

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CBD Increases BMI in Patients With Anorexia (LabRoots)

Preliminary findings suggest that CBD may help support weight gain and appetite in individuals with anorexia, potentially offering a gentler, plant-based option for addressing severe nutritional imbalances..

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Vitamin D Potentiates CB2-Mediated Anti-Tumor Responses in Prostate Cancer (ResearchGate)

CBD Synergizes With Methotrexate to Attenuate Rheumatoid Arthritis (International Immunopharmacology)

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A heartfelt thank you to all of the CBD brands whose generous support makes it possible for Project CBD to bring you the latest in plant medicine research and journalism each week. We are deeply grateful for your partnership in this important work.

The post Project CBD Newsletter: Cannabis inflammation research, CBD and gut-liver health, pain relief with CBD:THC formulations, and more appeared first on Project CBD.

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