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Project CBD Newsletter: Federally-Funded Study Links Cannabis Access to Opioid Overdose Reduction, CBD-Based Plastics, Psychedelic Risks, Runner’s High Neurochemistry, CBG for Arthritis, Terpenes for Diabetes and Cancer, and Cannabinoids for Fibromyalgia
This week’s newsletter covers a federally funded study on cannabis access and opioid overdose reduction, the potential of CBD-derived plastics, the risks of psychedelic therapy, the endocannabinoid system’s role in the runner’s high, and new research on CBG, terpenes, and cannabinoids for pain and inflammation.
Noteworthy Read
Cannabis Access Linked to Reduced Opioid Overdoses (Hemp Gazette)
A federally funded study found that medical cannabis dispensary access and recreational cannabis laws were associated with reduced non-fatal opioid overdoses among commercially insured adults. The findings support further research into cannabis access as a complementary harm-reduction strategy, while stopping short of proving cannabis legalization directly causes overdose reductions.
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More Noteworthy Reading
Hemp’s Next Market? CBD-Based Plastics (Cannabis Business Times)
Researchers have developed a CBD-derived thermoplastic, polycannabidiol carbonate, that could potentially compete with some petroleum-based plastics in packaging and higher-performance applications. The work points to a possible industrial market for hemp-derived CBD beyond wellness products, though major hurdles remain.
Why Some People Get Worse After Psychedelics (Medium)
This essay by Andrew Weisse examines why some people report worsening symptoms after psychedelic experiences, including psychological destabilization, poor preparation, inadequate support, and more. It’s a useful reminder that set, setting, screening, and follow-up care are important factors for psychedelic therapies.
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The Neurochemical Orchestra of the Runner’s High (Neuroscientist)
A new review examines the runner’s high as a coordinated neurochemical response involving endocannabinoids, endorphins, dopamine, serotonin, oxytocin, and related signaling systems. Some of the research focuses on the endocannabinoid system’s role in exercise-induced mood, analgesia, and reward.
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Research Round-Up
CBG Ameliorates Rheumatoid Arthritis Pathogenesis (Pharmaceuticals)
A preclinical study suggests CBG may reduce rheumatoid arthritis-related inflammation and joint damage through effects on immune signaling and inflammatory pathways. The findings add to early evidence around minor cannabinoids as potential anti-inflammatory agents.
Terpenes as Dual-Action Agents for Diabetes and Cancer (PubMed)
This review explores how plant-derived terpenes may act on overlapping metabolic, inflammatory, oxidative stress, and cell-signaling pathways involved in both diabetes and cancer. The paper highlights the growing interest in terpenes as multi-functional bioactive compounds.
Analgesic Effect of Cannabinoids for Fibromyalgia (Pain Physician)
A systematic review and meta-analysis evaluated the evidence for cannabinoids in fibromyalgia pain management, focusing on analgesic outcomes across available clinical studies. The findings suggest cannabinoids may offer pain-relief potential for some patients.
A heartfelt thank you to all of the CBD brands whose generous support allows Project CBD to shine a light on the latest plant medicine research and bring these important findings to our readers each week.
The post Project CBD Newsletter: Federally-Funded Study Links Cannabis Access to Opioid Overdose Reduction, CBD-Based Plastics, Psychedelic Risks, Runner’s High Neurochemistry, CBG for Arthritis, Terpenes for Diabetes and Cancer, and Cannabinoids for Fibromyalgia appeared first on Project CBD.
